Ketamine / K

Drug Class:
Dissociative anesthetic.
Individual drugs:
ketamine, ketalar, ketastat.
Common Terms:
Ketamine, K, Special K, cereal.
Standard Dose:
  • Ketamine is typically sold as a white powder (it looks like salt) typically by the vial.
  • Ketamine is typically snorted in small lines or as bumps.
  • It can be injected, swallowed or smoked.
The Buzz:
  • In small "bumps" K can cause relaxation and tingling sensations in the extremities.
  • In higher amounts one may go on an intense psychological journey or trip.
Overdose and other negative effects:
  • Immediate negative effects can be from entering a K-hole.
  • Physical harm from falling.
  • Nausea, especially when mixed with alcohol, or if food is eaten before using.
  • Physical addiction.
Dangerous Drug Combinations:
  • Mixing with other downers or alcohol.
HIV Medications & Ketamine
  • Protease Inhibitors (PIs) can increase the intensity and duration of K’s effects, with increased duration of sedation and higher blood pressure.
  • Elvitegravir/Cobicistat/TDF/FTC (Stribild) also has this effect.
  • If you use K and are on PIs you can go into a K-hole more easily.
  • Ritonavir/Norvir can increase risk of drug-induced hepatitis.
  • If ketamine makes you throw up within an hour of taking HIV medication, it is recommended to that you take a dosage of your HIV meds again.

Sex on Ketamine:
  • Feelings of connection and empathy are fairly common; however, you may feel more numb to pain, increasing the possibility of mucosal tears during rougher sex
  • Ongoing consent is an important consideration as it can be difficult to communicate with sex partners once high
  • Psychedelic drug effect sex drive and sexuality activity very differently for different people